Well SHB501CH is a sidetracking well deployed by Northwest Oilfield Company in the northern margin of Shuntuogole Low Rise in Tarim Basin. After sidetracking， more than 10 times of leakage occurred at the depth of 7706.65m with the leakage rate ranging from seepage to loss of return. Plugging with the methods of reducing drilling fluid density， bridge plugging and fast water loss had no obvious effects. Therefore， according to the leakage characteristics of the well， the one-sack chemical-solidifying plugging technology was proposed. The one-sack chemical-solidifying plugging material can form a concentrated compaction plug in the leakage channel， and it has good adaptability to the leakage channel， and can form dense plugging to improve the pressure bearing capacity； thus ensuring that one plugging material can plug various sizes and different types of leakage layers， so as to ensure the success rate of plugging. It was successfully used for plugging in Well SHB501CH. The one-sack chemical-solidifying agent follows the typical plugging process with operation， and is featured of wide adaption， stable performance， and long shelf life. It is ideal for plugging of low pressure broken formation， and will find broad applications