Geotechnical anchoring is the main measure of slope rock and soil reinforcement. Take an example of deformed slope reinforcement project in Heigou mining area of Jingtieshan mine, the slope stability analysis and supporting structure design calculation are made by using Slide software, then the comprehensive management engineering measures of groundsill by pre-stressed anchorage + slope top seepage prevention drainage + active and passive network protection + random anchorage are adopted for the deformed slope. This paper illustrates the general construction procedure and methods of the high slope pre-stressed anchor cable groundsill. The practice shows that the comprehensive prevention and control measures based on the pre-stressed anchor cable groundsill are good for the deformation control and the supporting effect of the deformed high slope.