This paper conducts an in-depth study on the drilling problems of soft mudstone strata in typical clastic rock salt deposits in Shashi salt deposits in Jiangling Sag in Jianghan Basin. Through the analysis of the characteristics of the saline-bearing strata in the study area and the actual drilling data of salt wells, the influence of soft mudstone strata on the safety, efficiency and quality of drilling engineering was systematically summarized. On this basis, a series of targeted drilling engineering technical countermeasures are proposed, such as the use of high-density undersaturated brine drilling fluid to balance formation pressure, cone bit + screw + inverted hole tool drilling tool combination, and the test drilling method of "retreat as advance". These countermeasures have been applied in the actual drilling process, which provides safety and quality assurance for subsequent construction, effectively reduces the probability of downhole complex conditions, and also provides an important reference for other drilling projects under similar geological conditions.