Aiming at the rock breaking problem in Xujiahe Formation, Xinchang-Hexingchang area of big hardness, poor drillability, high grindability and strong abrasiveness, a anti-drilling parameters profile of Xujiahe Formation was established, the engineering requirements of target layer and typical bit failure forms were analyzed. Combining research on rock breaking characteristics of different cutter types, the cutters arrangement method was optimized to a “circular and wedge” dual-row plane mixed cutter arrangement structure. Based on force analysis, the design of crown profile, blade structure and diameter retaining structure was carried out, forming a high guidance and force balance stability cutting structure. Ultimately, developed the customized PDC bits for Xujiahe difficult drilling formations. The on-site application effect has been significant, achieved average ROP of 4.88m/h with increase of 41%, and average travel depth of 347.16m with increase of 104%, providing a new technological means for accelerating drilling of 2nd Member of Xujiahe Formation Gas Reservoir in Xinchang-Hexingchang area.